PSD's Publications

Permanent URI for this collection

Longitudinal Cognitive and Physical Training Effectiveness in MCI, Based on the Experience of the Alzheimer's Hellas Day Care Centre

(SAGE, 2024-06) Eleni Poptsi ; Marianna Tsatali ; Christina Agogiatou ; Evaggelia Bakoglidou ; Georgia Batsila ; Dionysia Dellaporta ; Fotini Kounti-Zafeiropoulou ; Despoina Liapi ; Konstantinos Lysitsas ; Nefeli Markou ; Christos Alexander Mouzakidis ; Fani Ouzouni ; Chrysa Papasozomenou ; Aikaterini Soumpourou ; Magda Tsolaki ; Stavros Zafeiropoulos ; Maria Vasiloglou

This study assesses the effectiveness of a multicomponent Longitudinal Cognitive Training (CT) program plus physical exercise (PE) for people with Mild Cognitive Impairment (MCI). 155 people with MCI, completed a 3 years (3Y) CT+PE, whilst 133 were control. Neuropsychological assessment was performed at baseline and 3 years later, whilst CT+PE had additional annual assessments. According to the results, the 3Y CT+PE outperformed control in cognitive abilities (p < 0.002), and Activities of Daily Living (ADL) (p < 0.001), stabilized their functional performances between 1st and 2nd year, but worsened in working and verbal memory between 2nd and 3 rd year (p < 0.002). Control deteriorated in cognitive functions (p < 0.001) and ADL (p < 0.001) after 3 years, whilst 1.33% of the experimental and 13.53% of the control group progressed to dementia (p < 0.001). Longitudinal CT+PE improves cognitive performance and ADL in MCI and delay the progression to dementia.