PMID- 36645818
OWN - NLM
STAT- MEDLINE
DCOM- 20230202
LR  - 20230301
IS  - 1532-2491 (Electronic)
IS  - 1082-6084 (Linking)
VI  - 58
IP  - 3
DP  - 2023
TI  - Prospective Memory, Sustained Attention and Response Inhibition in Poly-Substance 
      Users Stable on Methadone Maintenance Treatment.
PG  - 397-405
LID - 10.1080/10826084.2023.2165410 [doi]
AB  - Background: Prospective memory and response inhibition are interrelated 
      constructs, though studied separately in the drug addiction literature. Also, 
      although sustained attention underlies response inhibition, its role in the 
      relation between these functions has been largely neglected. The limited research 
      on the cognitive effects of methadone-maintenance treatment (MMT) further 
      stresses the importance of investigating these effects. Objective: Therefore, the 
      current study focused on possible effects of MMT combined with long-term drug 
      abuse on all these functions. Thirty five long term opiate/poly-substance users 
      in MMT and thirty four drug-free controls were screened for socioeconomic status, 
      anxiety, depression and general, non-verbal intelligence and then tested on a 
      self-report measure of prospective memory and on the Go/No-Go task. Results: 
      Compared to controls, the MMT group scored worse in all functions assessed. 
      Prospective memory scores were also negatively related to Go/NoGo accuracy 
      scores. Conclusion: As predicted, (a) the MMT participants show impairments in 
      prospective memory, sustained attention and response inhibition and (b) 
      prospective memory, response inhibition and sustained attention are related 
      constructs. The results of this study could inform current rehabilitation and 
      relapse prevention cognitive training practices.
FAU - Redžepagić, Š
AU  - Redžepagić Š
AD  - Psychology Department, Sheffield University's International Faculty CITY College, 
      Thessaloniki, Greece.
FAU - Ladas, A I
AU  - Ladas AI
AUID- ORCID: 0000-0001-8833-4248
AD  - Psychology Department, CITY College, University of York Europe Campus, 
      Thessaloniki, Greece.
LA  - eng
PT  - Journal Article
DEP - 20230116
PL  - England
TA  - Subst Use Misuse
JT  - Substance use & misuse
JID - 9602153
RN  - UC6VBE7V1Z (Methadone)
SB  - IM
MH  - Humans
MH  - Methadone/therapeutic use
MH  - *Memory, Episodic
MH  - *Drug Users/psychology
MH  - *Substance-Related Disorders/psychology
MH  - Attention
MH  - Opiate Substitution Treatment/methods
OTO - NOTNLM
OT  - Go/No go task
OT  - Prospective memory
OT  - executive functioning
OT  - methadone
OT  - poly-substance users
OT  - response inhibition
OT  - sustained attention
EDAT- 2023/01/17 06:00
MHDA- 2023/02/03 06:00
CRDT- 2023/01/16 13:52
PHST- 2023/01/17 06:00 [pubmed]
PHST- 2023/02/03 06:00 [medline]
PHST- 2023/01/16 13:52 [entrez]
AID - 10.1080/10826084.2023.2165410 [doi]
PST - ppublish
SO  - Subst Use Misuse. 2023;58(3):397-405. doi: 10.1080/10826084.2023.2165410. Epub 
      2023 Jan 16.